Cancer cells penetrate deep into their environment
Researchers from the laboratory of Amit Pathak at the McKelvey School of Engineering found that cancer cells can sense a layer of cells beneath the top collagen layer on which they normally travel, while normal cells cannot. Their new study was published in Cell Reports.
Jumping genes in cancer cells open door to new immunotherapies
New research from the School of Medicine suggests that transposable elements in various cancers potentially may be used to harness novel immunotherapies against tumors that don’t typically respond to immune-based treatments.
Link named oncology division director
Daniel C. Link, MD, a highly regarded physician-scientist who treats patients with leukemia and also conducts innovative research, has been named director of the Division of Oncology in the Department of Medicine at the School of Medicine.
Two-pronged immunotherapy eliminates metastatic breast cancer in mice
Researchers at the School of Medicine have identified a way to sensitize metastatic breast cancer that has spread to bone to immunotherapy.
Possible treatment strategy identified for bone marrow failure syndrome
School of Medicine researchers have identified a possible treatment strategy for some bone marrow failure syndromes. These syndromes lead to an increased risk of developing dangerous infections, anemia and an increased risk of blood cancers.
Cells take on dual identities
Cells migrate to different tissues for a variety of reasons, including organ development, tissue repair and the spread of cancer. Researchers led by Amit Pathak at the McKelvey School of Engineering have found unexpected activity in the nucleus of healthy cells that provides new insight into cell mechanics.
Medicaid expansion improves childhood cancer survival
Medicaid expansion may improve outcomes for children with cancer, finds a new analysis from the Brown School and the School of Medicine. Researchers found there was a 1.5% increase in overall survival after 2014 in states that expanded access to Medicaid compared with states that did not.
Cancer patients who don’t respond to immunotherapy lack crucial immune cells
Researchers at Washington University School of Medicine have discovered that the difference between cancer patients who do and do not respond to immunotherapy may have to do with a particular immune cell. The findings could extend the lifesaving benefits of immunotherapy to more patients.
Computer model IDs roles of individual genes in early embryonic development
Software developed at Washington University School of Medicine can predict what happens to complex gene networks when individual genes are disrupted in specific ways.
Thompson receives National Cancer Institute grant to study cancer patients, caregivers
Tess Thompson, research assistant professor at the Brown School at Washington University in St. Louis, has received a five-year grant from the National Cancer Institute of the National Institutes of Health (NIH) to study unmet social needs of cancer patients and their caregivers, with the ultimate aim of improving outcomes for both.
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