Specialist enzymes make E. coli antibiotic resistant at low pH

Specialist enzymes make E. coli antibiotic resistant at low pH

New research from Arts & Sciences suggests that many “redundant” enzymes are actually specialists that ensure maximal growth across different environments. They also seem to increase resistance to antibiotics in conditions like those in the GI tract or urinary tract — raising concerns that current antibiotic susceptibility tests are inadequate.
How electricity-eating microbes use electrons to fix carbon dioxide

How electricity-eating microbes use electrons to fix carbon dioxide

Led by Arpita Bose, assistant professor of biology in Arts & Sciences, a Washington University team showed how an electricity-eating microbe takes up electrons from conductive substances like metal oxides or rust to reduce carbon dioxide. The work is described in the journal Nature Communications.
Washington People: Erik Herzog

Washington People: Erik Herzog

Erik Herzog, professor of biology in Arts & Sciences, studies the molecules, cells and circuits of mammalian circadian timing. He also supports and encourages younger neuroscience researchers, from elementary school all the way through doctoral programs.
Engineering proteins to help counter devastating diseases

Engineering proteins to help counter devastating diseases

Meredith Jackrel, assistant professor of chemistry in Arts & Sciences, recently received a five-year grant from the National Institutes of Health (NIH) and another from the Longer Life Foundation to study protein disaggregases —  evolved protein forms that mitigate protein misfolding — as a strategy to combat neurodegenerative diseases such as Alzheimer’s, Parkinson’s and ALS.
Blodgett awarded CAREER grant to study biosynthetic silence

Blodgett awarded CAREER grant to study biosynthetic silence

Joshua Blodgett, assistant professor of biology in Arts & Sciences, received a five-year $900,500 grant to support his research related to actinomycete bacteria. This type of bacteria produces a majority of current antibiotics and may harbor other useful small molecules that could be revealed by activating silent genes.
View More Stories