Author: Julia Evangelou Strait

Epidemiologists have designed a better method to quantify a woman’s risk of developing breast cancer, according to Graham Colditz, MD, DrPH, at Washington University School of Medicine in St. Louis. The model could help identify women at high risk of breast cancer who may benefit from prevention strategies that reduce the chances of developing the disease.

Two faculty members from Washington University in St. Louis have been named fellows of the American Association for the Advancement of Science, the world’s largest general scientific society. They are Michael J. Holtzman, MD (left), and Rohit V. Pappu, PhD.

Lee Ratner, MD, PhD, has been named the Alan A. and Edith L. Wolff Professor of Oncology at the School of Medicine. Shown here with Larry J. Shapiro, MD, dean of the School of Medicine, Ratner (right) is an oncologist and noted authority on retroviruses.

Roberto Civitelli, MD, the Sydney M. and Stella H. Schoenberg Professor of Medicine, has been elected president of the American Society for Bone and Mineral Research (ASBMR), the world’s leading scientific organization for bone health research.

Mitochondria are the power plants of cells, manufacturing fuel so a cell can perform its many tasks, and also are well known for their role in cell death. School of Medicine researchers and colleagues have shown that mitochondria also orchestrate events that determine a cell’s future, at least in the embryonic mouse heart. The study identifies new potential genetic culprits in the origins of some congenital heart defects. Shown is an image of a normal heart.

A laboratory testing kit that estimates the risk of breast cancer returning after anti-hormone treatment has received approval from the U.S. Food and Drug Administration (FDA). The technology is a step toward personalized medicine and could help standardize breast cancer diagnosis around the world. Researchers at the School of Medicine led the test’s development.

Doctors at the School of Medicine are investigating a new minimally invasive procedure to open blocked carotid arteries in patients whose poor health or advanced age makes the traditional open surgery too risky. Pictured are carotid arteries, which feed blood to the brain.

Breast cancer that spreads to other organs is extremely difficult to treat. Doctors can buy patients time, but a cure remains elusive. Now, researchers at the School of Medicine have shown that human breast tumors transplanted into mice are excellent models of metastatic cancer and could be valuable tools in the search for better treatments. Shown are human breast cancer cells (red) growing amid mouse cells (green).

Jeanne M. Nerbonne, PhD, the Alumni Endowed Professor of Molecular Biology and Pharmacology, has been named director of the Center for Cardiovascular Research.

Thomas B. Ferguson, MD, professor emeritus of cardiothoracic surgery at Washington University School of Medicine in St. Louis, died Sunday, May 26, 2013, of complications following a heart valve procedure. He was 90.