Fatty liver disease prevented in mice
Studying mice, researchers have found a way to prevent nonalcoholic fatty liver disease, the most common cause of chronic liver disease worldwide. Blocking a path that delivers dietary fructose to the liver prevented mice from developing the condition, according to investigators at the School of Medicine.
Washington People: Brian Nussenbaum
Brian Nussenbaum, MD, the Christy J. and Richard S. Hawes III Professor of Otolaryngology, is a surgeon dedicated to caring for patients with life-threatening head and neck cancers. Passions for teaching, research and patient safety have steered his career.
Study finds limited benefit for vitamin D in asthma treatment
Adding vitamin D to asthma treatment to improve breathing only appears to benefit patients who achieve sufficient levels of the supplement in the blood. Overall, the ability to control asthma did not differ between a study group that received vitamin D supplements and a group that received placebo. Mario Castro, MD, (left) led the study.
Mouse study offers new clues to cognitive decline
New research suggests that certain types of brain cells may be “picky eaters,” seeming to prefer one specific energy source
over others. The finding has implications for understanding the cognitive decline seen in aging and degenerative diseases such as Alzheimer’s and multiple sclerosis.
Genome regions once mislabeled ‘junk’ linked to heart failure
Large regions of the genome that were once referred to as “junk” DNA have been linked to human heart failure, according to research led by Jeanne Nerbonne, PhD, of Washington University School of Medicine in St. Louis.
$8 million to study gene-lifestyle interactions on heart health
School of Medicine researchers have received an $8 million grant to investigate the genetic and environmental roots of cardiovascular disease risk factors. The four-year grant will support the first large-scale, multiethnic statistical analysis of risk factors for cardiovascular disease that looks at lifestyle interactions with genes. Shown are principal investigators D.C. Rao, PhD, and Ingrid Borecki, PhD.
Castro named Wolff Professor of Pulmonary and Critical Care Medicine
Mario Castro, MD, has been named the Alan A. and Edith L. Wolff Professor of Pulmonary and Critical Care Medicine at the School of Medicine. He is a noted authority on asthma and other respiratory diseases.
Likely culprit in spread of colon cancer identified
New research at the School of Medicine and Vanderbilt University Medical Center has implicated a poorly understood protein called PLAC8 in the spread of colon cancer.
Journal honors breast cancer researcher
The Journal of Biological Chemistry has recognized School of Medicine researcher Ron Bose, MD, PhD, and his colleagues for work describing the combined structure of two proteins that, when bound together, drive growth of many breast cancers.
Imbalanced hearing is more than a mild disability
Asymmetric hearing is a difference between the two ears’ ability to detect and process sound. New studies indicate that people with asymmetric hearing experience greater communication difficulties than previously assumed. Researchers led by Jill B. Firszt, PhD, have received a $3 million grant from the National Institutes of Health (NIH) to study the effects of asymmetric hearing loss in adults and children.
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