Author: Leslie Gibson McCarthy

A new study from the School of Medicineshows that mutations in the gene TREM2 cause an energy shortage in the brain’s immune cells, leading to their failure to protect neurons from damaging clumps of protein.

Results of a small clinical trial show promise for treating a rare neurodegenerative condition that typically kills those afflicted before they reach age 20. The disease, called Niemann-Pick type C (NPC), causes cholesterol to build up in neurons, leading to a gradual loss of brain function.

The combination of a bacterium that normally lives in the gut and a protein-rich diet promotes a more tolerant, less inflammatory gut immune system, according to new research at the School of Medicine. The findings may potentially spell relief for people living with inflammatory bowel disease.

A new study from the School of Medicine shows that a particular gut microbe can prevent severe flu infections in mice, likely by breaking down naturally occurring compounds — called flavonoids — commonly found in foods such as black tea, red wine and blueberries.

A research group started in 2013 by two neuroscientists at the School of Medicine collected a massive amount of data on individual brains. The study’s subjects were the scientists themselves and eight others, all junior faculty or graduate students.

Using the gene editing technology CRISPR, scientists at the School of Medicine have shed light on a rare, sometimes fatal syndrome that causes children to gradually lose the ability to manufacture vital blood cells.

Siteman Cancer Center will begin seeing patients July 1 at its newest satellite location, Christian Hospital in north St. Louis County. Siteman Cancer Center is based at Barnes-Jewish Hospital and Washington University School of Medicine, and the new location is Siteman’s fifth in the St. Louis area.

Mapping the molecular structure of an RSV protein that interferes with the body’s ability to fight off the virus, researchers at the School of Medicine have found clues to how RSV causes disease. This could potentially lead to a vaccine or treatment.

A new study by anesthesiologists at Washington University School of Medicine in St. Louis and the University of Michigan Medical School sheds new light on the drug ketamine.

Stroke patients who learned to use their minds to open and close a device fitted over their paralyzed hands gained some control over their hands, according to a new study from Washington University School of Medicine in St. Louis