Genes linked to death from sepsis ID’d in mice
Bacteria in the bloodstream can trigger an overwhelming immune response that causes sepsis, a life-threatening condition. Now, researchers at Washington University School of Medicine in St. Louis have found genes that help protect the body’s cells from dying during sepsis, which could lead to new treatments.
More cancer patients get help to quit smoking
A new program funded through the Cancer Moonshot Initiative has doubled the number of patients at Siteman Cancer Center assessed for smoking — and increased by fivefold the percentage of cancer patients who smoke now taking medication to help them quit. The results have been published in the journal Translational Behavioral Medicine.
For malnourished children, new therapeutic food boosts gut microbes, healthy development
Researchers at the School of Medicine and the International Centre for Diarrhoeal Disease Research in Dhaka, Bangladesh, are developing a new approach to address childhood malnutrition. They are designing therapeutic foods aimed at repairing the gut microbiomes of malnourished children.
Fighting pancreatic cancer with immunotherapy
Researchers at the School of Medicine in St. Louis and Rush University in Chicago have found a compound that promotes a vigorous immune assault on pancreatic cancer. The findings, in mice, suggest a way to improve immunotherapy for the deadly disease in patients.
Understanding how tics are suppressed may help some at risk for tic disorders
Studying children shortly after they began experiencing tics, researchers at the School of Medicine discovered that although tics don’t go away, most children are able to suppress and control them. Understanding how they do that may provide insight to help others at risk for significant tic disorders.
Alzheimer’s missing link ID’d, answering what tips brain’s decline
Researchers at the School of Medicine have found that immune cells that typically protect neurons from damage may be the link between such early and late brain changes in Alzheimer’s disease. Breaking that link could lead to new approaches to delay or prevent the disease.
Aging delayed in older mice given blood component from young mice
Researchers at the School of Medicine have shown that supplementing older mice with an enzyme from younger mice extends life spans in the older ones.
Deadly tick-borne virus cured with experimental flu drug, in mice
Only a few cases of the newly discovered Bourbon virus have been reported, and two of them ended in death, partly because no specific treatments are available for the tick-borne illness. Now, researchers at Washington University School of Medicine in St. Louis have identified an experimental antiviral drug that cures mice infected with the potentially […]
Once thought to be asexual, single-celled parasites caught in the act
The single-celled parasite Leishmania can reproduce sexually, according to a study from the School of Medicine and the National Institutes of Health (NIH). The finding could pave the way towards finding genes that help the parasite cause disease.
To fight TB infection, early protection is crucial
Researchers at the School of Medicine and the Africa Health Research Institute have identified a master cell that coordinates the body’s immune defenses in the crucial early days after a tuberculosis infection. Boosting the activity of such cells could help reduce the millions of new infections that occur worldwide every year.
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