Stable home lives improve prospects for preemies

Stable home lives improve prospects for preemies

A new School of Medicine study has found that as premature babies grow, their mental health may be related less to medical challenges they face after birth than to the environment the babies enter once they leave the newborn intensive care unit.
$15 million supports quest for personalized leukemia therapies

$15 million supports quest for personalized leukemia therapies

Investigators at Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis have been awarded a $15 million grant to better understand the genetic changes that drive acute myeloid leukemia (AML), a deadly blood cancer, and predict patients’ responses to therapy. The findings also may enable investigators to develop more effective therapies tailored to patients, based on the genetic characteristics of their cancer cells.
Genes linked to Alzheimer’s risk, resilience ID’d

Genes linked to Alzheimer’s risk, resilience ID’d

A team led by researchers at the School of Medicine in St. Louis has identified a pair of genes that influence risk for Alzheimer’s disease. The genes — known as MS4A4A and TREM2 — affect the brain’s immune cells. They influence Alzheimer’s risk by altering levels of TREM2, a protein that is believed to help microglia cells clear excessive amounts of the Alzheimer’s proteins amyloid and tau from the brain.
Gut makeup could make diarrhea less likely

Gut makeup could make diarrhea less likely

Researchers at the School of Medicine have found the molecular signature of a healthy gut microbial community – the kind that can keep the intestinal bacteria Clostridium difficile (C. difficile) from overgrowing and causing diarrhea.
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