Cell-growth protein mTOR may help prevent diabetes

Ironically, diabetes researchers are hoping to promote the capability of mTOR that oncologists want to shut down: its ability to cause cells to reproduce by dividing into copies of themselves.

Lack of research and asset-building programs leaves many disabled persons in a financial and social limbo

The straightforward solution for many people living in poverty is building savings. For the 9 million disabled Americans living in poverty, the answer isn’t as simple. “The poverty rate among Americans with disabilities is nearly double that of persons without disabilities, and while there is a complex web of federal and state-based programs offering financial assistance to eligible persons with disabilities, policy rules often preclude the accumulation of assets, which are often key for exiting poverty,” says Michelle Putnam, Ph.D., assistant professor of social work at Washington University. “”New research and public policies have the potential to help people with disabilities to have greater economic resources and become more integrated into their communities.” More …

Researchers identify potential targets for new pain therapies

Neurons (shown here in green) fire more frequently in mice lacking Kv4.2 potassium channels.Studying mice, pain researchers at the School of Medicine have identified key components in the pain cascade that may provide targets for more effective analgesic drugs with potentially fewer side effects. Scientists have identified a potassium channel that plays a crucial role in what scientists call pain plasticity, the ability of molecules in the spinal cord to amplify or diminish the response to a painful stimulus.
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