Author: Jim Dryden

Although he wasn’t quite sure he wanted to go to medical school, ophthalmologist Todd P. Margolis, MD, PhD, now heads the Department of Ophthalmology and Visual Sciences. And he’s pioneering a phone app that could revolutionize the way people are screened for particular eye diseases.

Washington University researchers Melissa Krauss and Richard Grucza, PhD, led a team that analyzed data from all 50 states and found that higher cigarette taxes and policies prohibiting smoking in public places are associated with a decrease in alcohol consumption.

Researchers at Washington University School of Medicine in St. Louis have found that although a gene variant can prevent some young drinkers from developing alcohol problems, the gene’s protective effects can vanish in the presence of other teens who drink.

New research suggests that schizophrenia isn’t a single disease but a group of eight genetically distinct disorders, each with its own set of symptoms. The finding, in a study led by researchers at the School of Medicine, could be a first step toward improved diagnosis and treatment for the debilitating psychiatric illness.

Washington University researchers have developed algorithms to identify weak spots in tendons, muscles and bones prone to tearing or breaking. The technology, which needs to be refined before it is used in patients, one day may help pinpoint minor strains and tiny injuries in the body’s tissues long before bigger problems occur.

A method of growing human cells from tissue removed from a patient’s gastrointestinal (GI) tract eventually may help scientists develop tailor-made therapies for inflammatory bowel disease and other GI conditions. Pictured are Kelli L. VanDussen, PhD, and Matthew A. Ciorba, MD, members of a School of Medicine team that developed the method.

Washington University researchers have found that courses intended to better prepare high school graduates for college also drive some students to drop out. They report that policies increasing the number of required math and science courses are linked to a higher dropout rate.

Children diagnosed with depression as preschoolers are likely to suffer from depression as school-age children and young adolescents, research shows. Depressed preschoolers were 2.5 times more likely to suffer from depression in later school years than children who were not depressed at very young ages, according to School of Medicine researchers.

More efforts should be directed at promoting interventions that have the potential to prevent multiple chronic diseases and extend healthy lifespans. School of Medicine and other researchers write in Nature that economic incentives in biomedical research and health care reward treating disease more than promoting good health.

Regis James O’Keefe, MD, PhD, is a highly regarded orthopaedic oncologist. He comes to the School of Medicine from the University of Rochester School of Medicine and Dentistry, where he is the chair of orthopaedics and rehabilitation.