Caloric restriction appears to prevent primary aging in the heart

Vegetables are a staple of calorie restriction diets.Eating a very low-calorie yet nutritionally balanced diet is good for your heart. Studying heart function in members of an organization called the Calorie Restriction Society, investigators at the School of Medicine found that their hearts functioned like the hearts of much younger people. The researchers report their findings in the Jan. 17 issue of the Journal of the American College of Cardiology.

Region of DNA strongly associated with Alzheimer’s disease

An international team of researchers, led by investigators at the School of Medicine, are zeroing in on a gene that increases risk for Alzheimer’s disease. They have identified a region of chromosome 10 that appears to be involved in risk for the disease that currently affects an estimated 4.5 million Americans.

Variation in bitter-taste receptor gene increases risk for alcoholism

Alcoholism may be linked to taste.A team of researchers, led by investigators at the School of Medicine, has found that a gene variant for a bitter-taste receptor on the tongue is associated with an increased risk for alcohol dependence. The research team studied DNA samples from 262 families, all of which have at least three alcoholic individuals. Investigators report in the January issue of the American Journal of Human Genetics on the variation in a taste receptor gene on chromosome 7 called TAS2R16.

Telephone counseling for smokers focus of $1.3 million grant

WUSTL and BJC will provide new help for smokers who want to quit.People seeking help to quit smoking have many options, from support groups to nicotine replacement to prescription drugs designed to lessen the urge to light up. Now Washington University researchers and BJC HealthCare are testing another one: telephone counseling.

Light-sensing cells in retina develop before vision

Investigators at the School of Medicine have found that cells making up a non-visual system in the eye are in place and functioning long before the rods and cones that process light into vision. The discovery should help scientists learn more about the eye’s non-visual functions such as the synchronization of the body’s internal, circadian clock, the pupil’s responses to light and light-regulated release of hormones.

Tongue sensors seem to taste fat

Structure of the fatty acid receptor CD36French researchers recently reported that mice have a receptor in their tongues that can sense fat, and the presence of that receptor seems to drive the mice to crave fat in their diets. The research was based on work from scientists at the School of Medicine, where investigators previously had identified a protein receptor for fat and documented its function in recognizing and using fatty food.
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