Scientists unravel mechanisms in chronic itching

New research at the School of Medicine shows that chronic itching, which can occur in many medical conditions, is different from the urge to scratch a mosquito bite. Chronic itching appears to incorporate more than just the nerve cells that normally transmit itch signals. In the image shown, researchers identified elevated signaling (in red) in nerve cells involved in both itch and in pain.

School of Medicine celebrates launch of Taylor Family Institute

The Department of Psychiatry is hosting a celebration Tuesday, Oct. 1, to mark the official launch of the Taylor Family Institute for Innovative Psychiatric Research. The institute, dedicated to advancing the science underlying the diagnosis and treatment of psychiatric illnesses, was created with a $20 million gift from Andy and Barbara Taylor and the Crawford Taylor Foundation. Pictured are institute investigators.

Propofol discovery may aid development of new anesthetics

Researchers at the School of Medicine and Imperial College London are the first to identify the site where the widely used anesthetic drug propofol binds to receptors in the brain to sedate patients during surgery. Shown is a photoanalogue of propofol to identify where it binds to receptors. The small green circles show the site.

Rare gene variant linked to macular degeneration

Scientists at The Genome Institute at Washington University School of Medicine helped lead an international team of researchers who have identified a genetic mutation linked to age-related macular degeneration (AMD), the leading cause of blindness in Americans over age 50. Shown is an eye with signs of macular degeneration.

Incisionless surgery corrects swallowing disorder

By passing surgical instruments through a patient’s mouth, School of Medicine doctors have corrected a problem that prevented a woman from easily swallowing food and liquids. The operation is one of the first of its kind in the region performed through a natural opening in the body rather than an incision. Pictured is the surgical knife (blue) in the esophagus.

Alcohol abuse, eating disorders share genetic link

Part of the risk for alcohol dependence is genetic. The same is true for eating disorders. Now, School of Medicine researchers have found that some of the same genes likely are involved in both. They report that people with alcohol dependence may be more genetically susceptible to certain types of eating disorders and vice versa.
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