Author: Diana Lutz

Michael R. Brent and Tamara L. Doering examine data from the *C. neoformans* microarray.A team of collaborators, including two researchers from Washington University in St. Louis, has sequenced the genomes of two strains of the fungus Cryptococcus neoformans (C. neoformans), one which is virulent, the other harmless. This work provides researchers with clues on how the fungus does its dirty work and a host of genes to study for a better understanding of fungal pathogens in general. Estimates are that about 15 percent of people with HIV will suffer at least one life-threatening infection of C. neoformans. In Africa, that could be as much as 40 percent of HIV sufferers.

Christine Floss, Ph.D., and Frank Stadermann, Ph.D., examine data on the NanoSIMS in Compton Hall.A collaborative team of researchers including two from WUSTL have discovered what turns the lights out from space. They have discovered that organic carbon and amorphous silicates in interstellar grains embedded within interplanetary dust particles (IDPs) are the carriers of the astronomical 2175 Å extinction line, which occurs at a wavelength of 2175 Angstroms and blocks starlight from reaching the Earth.

*Arabidopsis thaliana*A team headed by Craig Pikaard, Ph.D., Washington University professor of biology in Arts & Sciences, has discovered a fourth kind of RNA polymerase found only in plants and speculated to have been a plant feature for more than 200 million years.

File PhotoBarbara Schaal will serve a four-year term as vice president of the highly prestigious group beginning July 1.She is “a premier scientist, and it is rewarding to the scientific community that she has been elected to such an important leadership role,” Chancellor Wrighton says.

Denise E. Wilfrey, Ph.D., David C. Van Essen, Ph.D., Jan A. Nolta, Ph.D., Jay W. Ponder, Ph.D. and more…

SchaalMembers of the National Academy of Sciences have elected Barbara A. Schaal, Ph.D., vice president of the Academy. Schaal is Spencer T. Olin Professor in Arts & Sciences in biology at Washington University in St. Louis. With her election, Schaal becomes the first woman ever elected vice president of the Academy.

Jeffrey H. Miner, Ph.D., James Cameron Monroe, Ph.D., and Lars Angenent, Ph.D.

He and his research team are developing an information-theoretic foundation for the design and analysis of imaging systems.

David Kilper/WUSTL PhotoProfessor Yoram Rudy (center), with Ph.D. student Yong Wang (left) and post-doctroal fellow Leonid Livshitz (right), with their ECGI system on a mannequin, comment on the cardiac data.Scientists at Washington University in St. Louis have developed the first mathematical model of a canine cardiac cell that incorporates a vital calcium regulatory pathway with implications for life-threatening cardiac arrhythmias, or irregular heartbeats. Thomas J. Hund, Ph.D., post-doctoral researcher in Pathology ( in Dr. Jeffrey Saffitz laboratory) at the Washington University School of Medicine, and Yoram Rudy, The Fred Saigh Distinguished Professor of Engineering at Washington University, have incorporated the Calcium/Calmodulin-dependent Protein Kinase II (CaMKII) regulatory pathway into their model, improving the understanding of the relationship between calcium handling in cardiac cells and the cell’s electrical activity.

Carrine Blank/WUSTL PhotoA WUSTL scientist suggests that Cyanobacteria arose in freshwater environments rather than in the sea.A geomicrobiologist at Washington University in St. Louis has proposed that evolution is the primary driving force in the early Earth’s development rather than physical processes, such as plate tectonics. Carrine Blank, Ph.D., Washington University assistant professor of geomicrobiology in the Department of Earth & Planetary Sciences in Arts & Sciences, studying Cyanobacteria – bacteria that use light, water, and carbon dioxide to produce oxygen and biomass – has concluded that these species got their start on Earth in freshwater systems on continents and gradually evolved to exist in brackish water environments, then higher salt ones, marine and hyper saline (salt crust) environments.