Immunotherapy-resistant cancers eliminated in mouse study
In a mouse study, researchers at Washington University School of Medicine in St. Louis have found that an antibody that targets the protein TREM2 empowers tumor-destroying immune cells and improves the effectiveness of cancer immunotherapy.
Clinical trial focuses on reducing overactive immune response in COVID-19
School of Medicine researchers are investigating whether a drug approved by the Food and Drug Administration to treat rare diseases of an overactive immune system could help critically ill patients hospitalized with COVID-19.
Vaccine prevents pneumonia, elicits high levels of protective antibodies
Researchers at Washington University School of Medicine in St. Louis have created a COVID-19 vaccine candidate from a replicating virus. This experimental vaccine has proven effective at preventing pneumonia in mice.
Alzheimer’s protein in blood indicates early brain changes
Researchers at Washington University School of Medicine have shown that levels of a specific protein in the blood rise as amyloid plaques form in the brain. The discovery could pave the way toward a blood-based test to diagnose Alzheimer’s disease before symptoms appear.
Two immunotherapies merged into single, more effective treatment
Researchers at Washington University School of Medicine have combined two types of immunotherapy into a single treatment that may be more effective and possibly safer than current immunotherapies for blood cancers.
Experimental drug shows early promise against inherited form of ALS, trial indicates
An experimental drug for a rare, inherited form of amyotrophic lateral sclerosis (ALS) has shown promise in a phase 1/phase 2 clinical trial conducted at Washington University School of Medicine and other sites.
Study to examine social media’s effects on stress during COVID-19 pandemic
Researchers at Washington University School of Medicine in St. Louis and Georgia Tech are leading a study using computer algorithms to identify stressors on social media linked to the COVID-19 pandemic.
Effort to screen potential COVID-19 antiviral drugs underway
The School of Medicine’s Jennifer A. Philips, MD, PhD, has set up a screening platform to test compounds for activity against the COVID-19 virus. Her lab has screened dozens of compounds and is prepared to accept more suggestions of promising candidate molecules.
Ida Early
For 38 years, Ida Early has contributed to many facets of Washington University. She reflects on the moments that have led her to this point as she prepares for retirement.
Folding@home’s fight against COVID-19 enlists big tech, gamers, pro soccer
The crowdsourced supercomputing project Folding@home, based at the School of Medicine, shifted focus months ago to coronavirus research. Now, units at Washington University and elsewhere, individuals and companies have joined the effort.
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