Author: Chris Amelung

Patricia Wolff examines a young patient in her pediatric clinic in Cap Haitien, Haiti.Swollen bellies, orange hair, listlessness and dull eyes — these are the traits of child malnutrition in Haiti, the poorest country in the Western Hemisphere and where roughly one of every three children is chronically malnourished. To try to change that statistic, Patricia Wolff, associate clinical professor of pediatrics, founded Meds & Food for Kids in 2004.

Listed below are this month’s featured news stories. • ADHD kids not receiving treatment (week of Aug. 2) • How tumors cloak themselves (week of Aug. 9) • New info about macular degeneration (week of Aug. 16) • Why steroids weaken bones (week of Aug. 23) • The brain’s ‘cold sheild’ (week of Aug. 30)

New research may finally settle a decades-old debate about how the kidney keeps valuable blood proteins from harmfully slipping into the urine, a serious health symptom that often precedes kidney failure. WUSM scientists discovered that a structure, known as the glomerular basement membrane, plays a key role in the process.

A woman trying to conceive a child may receive as many as 1,000 fertility-enhancing injections per year, but a recent discovery at the School of Medicine may help reduce the required number of fertility shots to about one per week.

These before (left) and after images show the effects of fumagillin-laden nanoparticles in a rabbit aorta.In laboratory tests, one very low dose of a drug was enough to show an effect on notoriously tenacious artery-clogging plaques. But it wasn’t so much the drug itself as how it was delivered. Fumagillin — a drug that can inhibit the growth of new blood vessels that feed atherosclerotic plaques — was sent directly to the base of plaques by microscopically small spheres called nanoparticles.

Dark areas (marked with arrows) in the first image show a process of bone renewal and strengthening. The second image shows a reduction in this process after a cortisone injection.Scientists are closing in on the solution to a persistent medical puzzle: why do high doses of cortisone, widely prescribed for asthma, rheumatoid arthritis and other inflammatory and autoimmune conditions, weaken bones? Researchers at the School of Medicine have identified osteoclasts, cells that dismantle old bone, as the essential link between osteoporosis and cortisone.

Summer practices can put young athletes at risk for heat exhaustion.Just before the new school season starts, football practice kicks off on fields around the country. Late summer workouts for football and other fall sports carry serious risks for heat-related illness. WUSM pediatrician Robert Kregenow explains how to spot heat exhaustion and how to prevent it.

VirginHerbert W. “Skip” Virgin has been named head of the Department of Pathology and Immunology at the School of Medicine. Virgin came to the department in 1990 as an instructor and became a professor in 2002. As the new department head, he becomes Edward Mallinckrodt Professor of Pathology and Immunology.

WellingThe Washington University Diabetes Center at Barnes-Jewish Hospital focuses on providing patients with the latest technology, treatments and clinical research. Some patients at the center are receiving a new diabetes drug that may give a welcome side effect — weight loss. Research lab supervisor Cris Welling began taking Byetta about 10 months ago and has lost 40 pounds.

TobinPatients managing diabetes can now get full diagnostics, treatment and education in one place — the Washington University Diabetes Center at Barnes-Jewish Hospital. The center will provide a new group-care and patient-education approach for patients with type 1 or type 2 diabetes, says Garry Tobin, medical director of the center.